Can it ever be economically justifiable to treat resection sites prophylactically during surgery, with air leak prevention measures? It’s not a difficult algorithm to establish, but it appears never to have been done in a way that completely provides the answer, nor helps when assessing when to seal and when to leave. It’s perhaps not surprising therefore that surgical practice is so highly variable; some surgeons seal routinely, others seal when they find an air leak, others seal in specific procedure types and of course some never adopt a sealant methodology at all. What seems plainly to be the case from experience of observing the practice of many centres is that duration of patient stay is usually directly linked to removal of drains, which is in turn usually directly linked to existence of air leaks. Yet in post marketing surveillance studies commissioned by Tissuemed it seems that other factors are at play. Even when patients were declared air-leak free they still regularly remained in hospital for days thereafter, despite the fact that air leaks are identified as the principle reason for continued hospitalisation. So what’s occurring here? We’d like to know and in order to find out we are looking for thoracic centres in UK or Eu, with whom we can work to uncover the real-world economics concerning reduction of post-operative air leaks and optimisation of the post-operative treatment algorithm. If you are a clinician or nurse working in such a centre and would like to be involved in this project please email Tissuemed here and we will make contact.