Neuro/Spinal Publications

Peer-reviewed Journal Publications

A purely synthetic and biodegradable material for repair of cerebrospinal fluid rhinorrhoea

Surda P, Syed I, Modayil P.C, Little SA, Toma A

Department of Otolaryngology, St George’s Hospital, London, UK

Findings from a series of patients where TissuePatchDural™ was used to successfully treat cerebrospinal fluid rhinorrhoea – CSF leaks through the nasal cavity.

Two alternative dural sealing techniques in posterior fossa surgery

Schiariti M, Acerbi F, Broggi M, Tringali G, Raggi A, Broggi G, Ferroli P

Carlo Besta Institute, Milan, ITALY

Published in Surgical Neurology International. Two alternative dural sealing techniques in posterior fossa surgery: (Polylactide‑co‑glycolide) self‑adhesive resorbable membrane versus polyethylene glycol hydrogel.

Preliminary retrospective study on 119 consecutive high-risk patients.

Ferroli P, Acerbi F, Broggi M, Schiariti M, Albanese E, Tringali G, Franzini A, Broggi G

Carlo Besta Institute, Milan, ITALY

This first publication from the world-renowned Carlo Besta Institute presents their impressive experience using TissuePatchDural™ for achieving dural closure in a series of 119 high risk patients.

Intraoperative sealing of dura mater defects with a novel, synthetic, self adhesive patch

von der Brelie C, Soehle M, Clusmann HR

University of Bonn, GERMANY

A single centre series in 25 patients presenting excellent product safety with follow-up for 12 months.

Use of a new absorbable sealing film for preventing postoperative cerebrospinal fluid leaks

Della Puppa A, Rossetto M, Scienza R

University of Padova, ITALY

Published in the British Journal of Neurosurgery in 2010, neurosurgeons detailed the first clinical experience with TissuePatch for dural closure. 100% watertight closure was achieved with patients followed for up to 9 months.


A single centre experience with two surgical sealants for CSF leak prevention in Posterior Fossa surgery

Palin MS, van Hille P

Department of Neurosurgery, Leeds General Infirmary, UK

Review of the safety and efficacy of a new sealant film for adjunctive closure of the dura mater in a series of patients undergoing posterior fossa surgery.

Cerebrospinal Fluid Rhinorrhea: Preventive Strategy in Transnasalsphenoidal Surgery

Berlucchi S, Gerunda A, Scanarini M

Operating Unit, Endocrine Neurosurgery, University Hospital of Padua

Avoidance of CSF leak after Microvascular Decompression with Clinical Use of a New Synthetic Adhesive Film

Ferroli P, Angius D, Acerbi F, Tringali G, Broggi M, Broggi G, Franzini A

Carlo Besta Institute, Milan, ITALY

Dural Reconstruction in Surgery of the Posterior Cranial Fossa

Nuzzi D, Masotto B, Ricci UM, Turazzi S

Department of Neurosurgery at the Integrated University Hospital, Verona

Intraoperative sealing of dura mater defects with a new, purely synthetic, self adhesive patch – an application study

von der Brelie C., Clusmann H.

Neurosurgical Department ; University of Bonn Medical Center