TissuePatchDural Logo

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TissuePatchDural™ is a surgical sealant film, specifically designed to reinforce closure of the Dura Mater to achieve a watertight seal.

It is a self-adhesive film comprising synthetic polymers that are encountered in everyday surgery. It contains no human, bovine or porcine material,

It is multi-layered, incorporating structural and adhesive absorbable components.

The active component within TissuePatchDural™ is Tissuemed’s proprietary TissueBond™ bioadhesive technology. This bonds the film to proteins on the tissue surface within a minute, providing immediate support and an effective watertight closure during the natural healing process.


TissuePatchDural™ requires no advance preparation and can be applied straight from the pack.

TissuePatchDural™ is transparent, allowing post-application wound visualisation.

It is available in a range of sizes and shapes and can be cut to shape to suit clinical requirements.

Note: TissuePatchDural is not indicated for use as a dural substitute or replacement, but can be used in combination with such materials to achieve watertight closure.


TissuePatchDural™ is indicated to seal and reinforce against Cerebrospinal Fluid (CSF) leakage during surgical repair of the Dura Mater in Cranial, Spinal and Transnasal closure.

By helping surgeons to achieve a watertight closure the product helps in the avoidance of post-operative complications associated with CSF leaks. This means it can contribute to shorter patient stays and reduced healthcare costs.

Dural closure with TissuePatchDural - close-upProduct Handling

The photographs illustrate the typical use of TissuePatchDural™ to reinforce a sutured Dura – sealing gaps and suture holes.

Simply Open and Apply

Three simple steps to achieving a watertight result

Step 1: Open and dispense

Dural closure with TissuePatchDural - close-upProduct HandlingCarefully peel apart inner pouch in sterile field. Gently remove the patch with forceps, remembering that it is at its most fragile in its pre-application state. No preparation is necessary and the patch is now ready to use. Ensure the logo is facing upwards and is readable throughout placement.

Step 2: Place

Dural closure with TissuePatchDural - close-upProduct HandlingTarget tissue should be gently swabbed, but does not need to be absolutely dry. Place the patch gently on the tissue. Aim for a minimum 1cm margin from suture line to the edge of the patch. If required, limited patch repositioning is possible if performed immediately at this stage.

Step 3: Adhere to Target Tissue

Dural closure with TissuePatchDural - close-upProduct HandlingHold a damp swab over the patch, “encouraging contact” with tissue surface for 60 seconds. If reassurance is needed, repeat the exercise but do not reposition or move the same patch. Overlapping patch edges to achieve coverage is possible. Note however that patch-over-patch adhesion is less strong than patch over tissue.

Hints and Tips

1. Can it be cut to shape or size?

Yes. To minimise handling, it is suggested that patch be cut in the sleeve first before removing.

Can TD be cut to shape or size?

2. Does it need to be wet before application?

No. Wetting prior to use is not strictly required. However, hydration is not contraindicated and can enhance handling characteristics.

Does TD need to be wet before application?

3. Should adherence be tested before closure?

Usually patch adherence is visually apparent, but if confirmation is required do not use sharp instruments as these may risk “puncturing” the patch.

Should adherence be tested before closure?

Size Guide/Ordering

Size Code
5 x (25 x 50 mm) TD-01M
5 x (50 x 50 mm) TD-02M
5 x (50 x 100 mm) TD-03M
5 x (100 x 100 mm) TD-04M

TissuePatchDural Sizes