TissuePatch Logo for ENT/Head and Neck Surgery

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ENT/Head and Neck Applications

TissuePatch™ is a synthetic, self-adhesive surgical sealant for the avoidance and resolution of leaks in surgery. It is particularly effective in adjunctive closure of tissue to minimise blood, saliva and chyle leaks during ENT surgery procedures.

TissuePatch™ is fully synthetic, containing no human, bovine or porcine material.

It is multi-layered, incorporating structural and adhesive absorbable components.

The active component within TissuePatch™ is Tissuemed’s proprietary TissueBond™ bioadhesive technology. This bonds the film to proteins on the tissue surface within a minute, providing immediate support and an effective airtight closure during the natural healing process.


TissuePatch™ requires no advance preparation and can be applied straight from the pack.

TissuePatch™ is transparent, allowing post-application wound visualisation..

At only 40 microns thick, TissuePatch™ delivers an effective therapeutic solution for only a tiny amount of foreign material.

It is available in a range of sizes and shapes and can be cut to shape to suit clinical requirements.

Note: TissuePatch™ is NOT indicated for direct use in the mouth on Oral Mucosa


TissuePatch™ is indicated to seal and reinforce against leaks during surgical repair of the tissues in ENT Surgery.

Tissuemed has extensive experience using Tissuepatch in ENT surgery; thyroid surgery, neck resections, parotid surgery and laryngectomy.

By helping surgeons to achieve watertight closure the product helps in the avoidance of post-operative complications associated with saliva and chylous leaks. This means it can contribute to shorter patient stays and reduced healthcare costs.

Simply Open and Apply

How to Use it

Three simple steps to achieving a watertight result (open surgery)

Step 1: Open and dispense

Dural closure with TissuePatchDural - close-upProduct Handling

Carefully peel apart inner pouch in sterile field. Gently remove the patch with forceps, remembering that it is at its most fragile in its pre-application state. No preparation is necessary and the patch is now ready to use. Ensure the logo is facing upwards and is readable throughout placement.

Step 2: Place

Product HandlingTarget tissue should be gently swabbed, but does not need to be absolutely dry. Place the patch gently on the tissue. Aim for a minimum 1cm margin from suture line to the edge of the patch. If required, limited patch repositioning is possible if performed immediately at this stage.

Step 3: Adhere to Target Tissue

Hold a damp swab over the patch, “encouraging contact” with tissue surface for 60 seconds. If reassurance is needed, repeat the exercise but do not reposition or move the same patch. Overlapping patch edges to achieve coverage is possible. Note however that patch-over-patch adhesion is less strong than patch over tissue.

ENT application:

TissuePatch™ can be manipulated into position over target suture line or tissue, when small swabs can be employed to gently locate and affix it to the tissue surface. As with all patch applications, bonding to tissue surface is not instant, so may require gentle pressure and a steady “dabbing” action to achieve fixation. Images below show an end result with TissuePatch™ firmly adherent and covering all potential leak sites.

Neck SurgeryNeck Surgery
Neck SurgeryNeck Surgery

 Hints and Tips

1. Can it be cut to shape or size?

Yes. To minimise handling, it is suggested that patch be cut in the sleeve first before removing.

Can TD be cut to shape or size?

2. Does it need to be wet before application?

Wetting prior to use is not strictly required. However, hydration* can enhance the handling characteristics of TissuePatch.

*For further information on hydrating Tissuemed see the guidance sheet provided here

Does TD need to be wet before application?

3. Should adherence be tested before closure?

Usually patch adherence is visually apparent, but if confirmation is required do not use sharp instruments as these may risk “puncturing” the patch.

Should adherence be tested before closure?

Size Guide/Ordering

Size Code
5 x (25 x 50 mm) TP-01M
5 x (50 x 50 mm) TP-02M
5 x (50 x 100 mm) TP-03M
5 x (100 x 100 mm) TP-04M
5 x (30 x 80 mm) TP-05M
5 x (25 x 100 mm) TP-07M