Tissuemed has updated its guidance for use document and made it available on its website here. The pdf document shows only minor changes from previous versions, but of note is the company’s repeating of the guidance that the swab used to hold its product in approximation with the tissue is better to be moistened rather than dry. This is a relatively insignificant change to original guidance, and more of a “hint and tip” than a directive. However it is based on feedback from surgeons who state that the material conforms more quickly and completely to complex tissue surfaces when a moist swab is used to hold it in place for the required period of time.